Khloé Kardashian has previously tried to shut down speculation that she used the weight-loss drugs to help her slim down.

But she and her sister Kim Kardashian, 42, were beset by fan speculation that they had been using a popular anti-diabetes drug when they posted pH๏τos of their newly chiseled abs on Monday.

Several fans and critics called out the famous sisters for supposedly using weight-loss substances, despite their denials and a lack of concrete evidence that they had used Semagluti

Some fans even went as far as to accuse the reality stars of shooting an ad for Ozempic due to their significant weight loss.

‘An Ozempic ad is what I see here,’ wrote one accusatory account in the comments to their Instagram posts.

Another person joked, ‘Save some insulin for the people who actually need it,’ though the drugs that many fans speculated that they had been using are distinct from the insulin that many diabetic people require.

Others complained more generally about the sisters’ weight loss, insisting that they were ‘too slim.’

One particularly cruel comment appeared to be directed at Khloé: ‘Her hands look too thin eat something you look hungry.’

Another user joked that Khloé was ‘barely flexing,’ while Kim was ‘holding it in.’

Another user bemoaned the ‘money spent on those bodies.’

Other users complained more generally about Kim and Khloé’s recent weight loss, though Khloé’s physical transformation has been more gradual, and she has regularly highlighted her intense workouts for years.

‘What are yall trying to see who can show all their ribs the fastest???wtf,’ commented one person.

Others sounded nostalgic for the sisters’ curves of years past.

‘When are you guys gonna bring curvy back….asking for a friend,’ read one critical comment.

Although Khloé described herself and Kim as Calabasas girls in her caption, one user suggested ‘Ozempic girls’ might be more accurate.

Another person simply wrote, ‘Somebody please feed them 😬.’

Ozempic is manufactured by Danish pharmaceutical giant Novo Nordisk and costs around $900 per dose.

The injectable version can be used on the stomach, thigh or arm, and it quickly works to suppress a person’s appeтιтe, which can be useful in allowing them to shed weight.

It is currently only approved by the FDA as a type 2 diabetes treatment, but many medical providers have begun prescribing it off label as a weight-loss drug recently, and it has skyrocketed in popularity among wealthy customers looking to slim down.

However, the rush of rich people looking to buy the drug has created shortages that harm diabetic people who most need it for their health.